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How THC and CB are similar and different!
THC and CBD are easily the two most common cannabinoids we hear about and see in the industry then and now/today

They are both produced by the cannabis plant, in the glandular trichomes of the unfertilized female flower, in their acidic forms!

so actually they are termed phyto-cannabinoids, whereas endocannabinoids

are the cannabinoid-like molecules we produce endogenously that interact with our endocannabinoid system

lets take a look at THCs and CBDs structure

they contain the same # of Carbon, oxygen, and hydrogen atoms, (C21H30O2)

their mass is the same at 314 grams per mol

they almoooostt look identical, However, there is one tiny difference,

THC contains an ether which created a cyclical ring, whereas THC has a hydroxyl group

Oddly enough this is the difference between getting high and not getting high lol

And this is likely why CBD has a broader spectrum of pharmacological effects than THC

its More like a tiny big difference, knawimsayin

so, like we kinda hinted to, THC is the main intoxicating psychoactive component of cannabis

It has this effect on us because it binds to our CB1 receptors,

its what’s known as a weak partial agonist

on the otherhand, although CBD is psychoactive, its NON INTOXICATING – its psychoactive because it interacts with and modulates our nervous system

and yes, it ALSO interacts with the CB1 receptors, but in a different way from THC

CBD binds to another area on the receptor, which causes the receptors to release THC.

CBD is what’s known as a Negative allosteric modulator on CB1

CBD interacts with a variety of other receptors in our body too, which will be in that video

Combining CBD and THC decreases the psychoactivity and other side effects of THC, while enhancing some of THC’s benefits.

And when you get the CBD to THC ratio to be about a 1:1, or higher on the CBD side

it’s a great way to use cannabis for relief without having to worry about getting high

I hope you learned something and ill see ya next time!

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Mike Tyson, the former heavyweight champion and cannabis mogul (with ear-shaped gummies) tells Forbes how pot changed his life—and the secret weapon that will help him smoke Jake Paul in their fight.

While Iron Mike was prone to being his own hype man as a fighter, he’s not far off with his claims about his budding cannabis company. Tyson 2.0 sells marijuana products—including flower, vapes and edibles made in the shape of Evander Holyfield’s ear, which Tyson notoriously bit during a 1997 match—in 20 states across the U.S., and in Amsterdam, Barcelona and Thailand. The company, through a partnership with PHCANN International in Macedonia, is in the process of launching in Germany’s newly legalized adult-use market as well as the U.K.’s highly restrictive medical marijuana industry.

Tyson 2.0 works off a licensing model, cutting deals with franchisees who grow, manufacture, and sell his branded cannabis products. In 2023, the brand generated $150 million in revenue, Forbes estimates, with about 30% coming from cannabis sales and the rest from accessories, CBD, nicotine vaporizers and other products.

Tyson 2.0’s flower is branded with names drawn from his legendary boxing career, including Dynamite Cookies (his first nickname was Kid Dynamite) and Knockout OG (Tyson won 44 of his 50 boxing career wins by KO). But the company’s flagship product Mike Bites—the edible in the shape of Holyfield’s half-bitten ear—was developed by Tyson’s wife, Kiki.

Read the full story on Forbes:
https://www.forbes.com/sites/willyakowicz/2024/04/26/mike-tyson-on-becoming-a-heavy-hitter-in-weed/

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Nevertheless, need is enhancing for CBD after it was maded popular in 2013 by the CNN unique, Weed. In Weed, five-year-old Charlotte Figi treats her severe kind of epilepsy, Dravet Syndrome with CBD, minimizing her seizures from 300 a week to just one a day. Unlike THC, CBD does not generate a high and also it also counteracts the results of THC. So what is this miracle substance and also how does CBD Oil For Copd Dosage function?

Thousands of men and women who struggle with PTSD have actually discovered relief as well as quality with CBD items. CBD’s ability to naturally enhance the price of serotonin manufacturing and all at once bind with serotonin receptors bypasses the decreased existence of cortisol. Of all of the disorders of the brain that create stress and anxiety- as well as depression-related conditions, the bulk have completion outcome of decreased serotonin task; CBD has the ability to soothe a lot of these conditions with near-pharmaceutical effectiveness.

CBD Oil For Copd Dosage also regulates the endocannabinoid system, to a lesser level. Via retrograde signalling, or signalling backwards, the endocannabinoid system finishes the favorable and also unfavorable responses loops in most of our body’s systems, consisting of the mind. Over stimulation of adrenaline has the impact of raising the endocannabinoid production in those neurons, which then permits the positive increase in adrenaline production that creates hypersensitivity to adrenaline.

It codes for an enzyme that breaks down endocannabinoids (eCBs) for the purpose of avoiding the kind of signalling that triggers a synapse to be strengthened. This is necessary because nerve cells are supposed to develop prenatally, but not come to be enhanced or strengthened till information from the world could start to promote them and route their development so they could best function worldwide.

Researchers claim CBD might aid in CBD Oil For Copd Dosage a number of means. First, it inhibits the CB1 receptor that endocannabinoids (eCBs) bind with, so even if there’s way too many eCBs, they will not have the ability to have as much of a result on reinforcement. Second of all, CBD binds to numerous proteins that could be thought of as the breaker of our hereditary code: they regulate exactly what obtains turned on and also what doesn’t. The precise process of this task is not yet well comprehended, however administration of CBD in rats demonstrated elevated expression of this genetics in cells that previously weren’t revealing it in any way.

CBD oil is a cannabis oil (whether stemmed from marijuana or commercial hemp, as the word cannabis is the Latin genus name for both) that has significant quantities of cannabidiol (CBD) included within it. Our CBD items and also essences are originated from commercial hemp, so they could be considered CBD-rich hemp oil, hemp acquired CBD oil, CBD-rich cannabis oil, or simply “hemp essences” because they commonly contain far more than simply CBD. Again, cannabis does not mean cannabis yet is the genus name as well as basic umbrella term which all kinds of cannabis and hemp autumn under. The type of cannabis we make use of for our CBD as well as hemp removes is commercial hemp; we do not sell cannabis.

CBD has actually been in the news prior to, as a possible therapy for epilepsy. Research study is still in its very early days. Scientists are checking just how much CBD has the ability to reduce the number of seizures in individuals with epilepsy, as well as exactly how safe it is. The American Epilepsy Culture specifies that cannabidiol study supplies expect seizure disorders, which study is presently being carried out to much better recognize risk-free usage.

A study from 2016 collaborated with 214 individuals with epilepsy. The research participants included dental dosages of 2 to 5mg of CBD per day to their existing anti-epilepsy drugs. The research study’s scientists monitored the participants for 12 weeks, taping any negative side effects and checking on the frequency of their seizures. In general, CBD Oil For Copd Dosage individuals had 36.5 percent fewer seizures per month. Nevertheless, severe negative results were videotaped in 12 percent of the participants.

Understanding More About CBD Oil For Copd Dosage

A number of CBD makers would certainly not talk on the document for fear

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Bong Appetit host Matt Zimbric‘s latest adventure leads him to an experimental cannabis cocktail party in Los Angeles. Matt meets with leading mixologist Daniel K. Nelson of (Partner, The Black Cat) to learn the basics and some new tricks of the trade when it comes to making cocktails with cannabis.

After jumping into a 1972 Cadillac hearse party limo (as one does in LA), they hit up Aaron Justis (President, Buds & Roses) to research, shop and sample the perfect bouquet of ganja goods—may we recommend Silverback Grape Ape and Oregon Silver?—to infuse into their cocktails and food. On the menu: California fresh herb salad and sous-vide steak with cannabis compound butter.

Later, Daniel demonstrates how to get the right dosage to ensure that your cannabis cocktails don’t resemble dirty bong water and that your guests leave in a state of nirvana after having the the high-class meal of a lifetime. We’ll spark to that.

Up Next:
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Guest: Matt Rife
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